Search results for "Strenuous exercise"

showing 5 items of 5 documents

Physical Exercise and DNA Injury

2017

Regular, low-intensity physical activity is currently advocated for lowering the risk of developing many acute and especially chronic diseases. However, several lines of evidence attest that strenuous exercise may enhance inflammation and trigger the generation of free radical-mediated damage, thus overwhelming the undisputable benefits of regular, medium-intensity physical activity. Since reactive oxygen species are actively generated during high-intensity exercise, and these reactive compounds are known to impact DNA stability, we review here the current evidence about strenuous exercise and DNA injury. Despite the outcome of the various studies cannot be pooled due to considerable variat…

0301 basic medicinemedicine.medical_specialtybusiness.industryDNA damageStrenuous exercisePhysical activityPhysical exercise030229 sport sciences03 medical and health sciences030104 developmental biology0302 clinical medicinePhysical medicine and rehabilitationDNA stabilitymedicineExercise intensityExertionIntensive care medicinebusinessDNA injury
researchProduct

Strenuous exercise and the heart: are we not seeing the wood for the trees?

2014

The health benefits of regular moderate-intensity physical activity (e.g. brisk walking, jogging) are well established and include, among others, a lower risk of all-cause mortality and cardiovascular disease (CVD). Yet whether such benefits, especially with regard to CVD, are also conferred by higher exercise levels is a matter of growing controversy in the medical literature. For instance, Guash and Mont recently expressed understandable concern about the link between regular strenuous endurance exercise. 4.036 JCR (2014) Q1, 29/123 Cardiac and cardiovascular systems UEM

Cienciamedicine.medical_specialtyEducación física - Evaluaciónbusiness.industryStrenuous exercisePhysical ExertionHeartEjercicio físico - FisiologíaCardiovascular DiseasesPhysical therapymedicineHumansCardiology and Cardiovascular Medicinebusinesshuman activitiesCiencias médicasExerciseInternational journal of cardiology
researchProduct

Proteolytic capacity in mouse cardiac muscle following strenuous exercise

1981

Proteolytic capacity in mouse cardiac muscle was analyzed 1, 3, and 6 days after exhaustive intermittent or submaximal prolonged running. No significant changes were recorded in the activities of acid or alkaline proteases, β-glucuronidase or trypsin inhibitor. Similarly, no changes were found in the rates of acid or neutral autolysis.

medicine.medical_specialtyAutolysis (biology)ProteasesTime FactorsStrenuous exerciseTrypsin inhibitorPhysical ExertionCoronary DiseaseMiceCellular and Molecular NeuroscienceInternal medicinemedicineAnimalsskin and connective tissue diseasesMolecular BiologyPharmacologyChemistryMyocardiumCardiac muscleCell Biologymedicine.anatomical_structureEndocrinologyBiochemistryMolecular Medicinesense organsPeptide HydrolasesExperientia
researchProduct

Hemodynamic Effects of Ventricular Pacing

1985

Fixed rate ventricular pacing is used in most cases of implanted pacemakers. It does not usually create considerable hemodynamic problems, as the heart, by its adaptation mechanism, is capable of varying its pump performance to meet the metabolic needs[1,3].

medicine.medical_specialtyEjection fractionbusiness.industryInternal medicineStrenuous exerciseModerate exerciseCardiologyMedicineHemodynamicsStroke volumeVentricular pacingbusinessHemodynamic effects
researchProduct

Physical activity - an important preanalytical variable

2014

The concentration of several biochemical and hematological biomarkers is strongly influenced by a number of preanalytical variables. Several lines of evidence attest that short, middle, and long-term exercise, as well as the relative intensity of physical effort (from mild to strenuous), may influence a broad array of laboratory variables. The amount of extracellular release and clearance from blood of most of these biomarkers is markedly influenced by the biological characteristics of the molecule(s), level of training, type, intensity and duration of exercise, and time of recovery after training. It is hence noteworthy that test results that fall outside the conventional reference ranges …

medicine.medical_specialtyStrenuous exerciseClinical BiochemistryPhysical activityphysical activityPhysiologyContext (language use)Physical exerciseReviewDiseasepreanalytical variables; exercise; physical activitypreanalytical variablesbiomarkers; training; plasma volume; metabolism; cellular damagecellular damageHumansMedicineDiagnostic ErrorsPlasma VolumetrainingexercisebiologyRelative intensityAthletesbusiness.industryBiochemistry (medical)biomarkersbiology.organism_classificationPhysical therapyNarrative reviewbusinessmetabolismBlood Chemical AnalysisBiochemia Medica
researchProduct